The Chong Lab
Department of Chemistry at the University of Pittsburgh
We are a collaborative group of scientists who work at the interface of chemistry, physics, and biology to investigate how molecular dynamics and kinetics govern biomolecular function. Our research emphasizes the development and application of advanced simulation methods to capture atomistic views of rare biological events, such as protein binding and large-scale conformational transitions. We also develop simulation strategies to rationally modulate protein switching kinetics. Our group is the primary developer of WESTPA, a software package for weighted ensemble simulations of rare events, as well as the implicitly polarized AMBER force fields (ff15ipq/ff15ipq-m).
Recent News
Baily Ford Graduate Student Highlight
Chong Lab member, Baily Ford, has been highlighted by the University of Pittsburgh Department of Chemistry. Read the highlight here!
Anthony Bogetti awarded Best Graduate Student Paper from the University of Pittsburgh
Congratulations to Anthony Bogetti for being awarded the best graduate student paper from the University of Pittsburgh Department of Chemistry in 2024. Check...
Darian Yang Publishes PNAS Paper on the Flexibility of HIV Capsid
Congratulations to Darian Yang for his PNAS paper on the flexibility of the viral HIV capsid. Check out the paper here!
Open Science Conversations: An Interview with Lillian Chong, University of Pittsburgh
ACS Axial has interviewed Dr. Lillian Chong regarding her research and views on open source software in the scientific community. Check it out!